Journal of Advances in Health and Medical Sciences
Journal ISSN: 2517-9616
Article DOI:
Received: 12 April 2017
Accepted: 20 May 2017
Published: 30 June 2017
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  • Calcipotriol: A promising treatment for hand eczema

Ratchasin Pongprasert, Premjit Juntongjin

Published online: 2017


Hand eczema is a common dermatologic condition which has a poor response to conventional therapies. Calcipotriol, topical vitamin D analogue has been approved in the treatment of psoriasis and was reported to achieve a beneficial effect in the treatment of many other inflammatory diseases. The aim of this study is to assess the efficacy and safety of Calcipotriol ointment in the treatment of chronic hand eczema. Six patients were treated with calcipotriol twice daily for 2 weeks. The efficacy was evaluated by HECSI and patient’s self-assessment. Any adverse reaction was recorded during the experiment. The result revealed a statistical improvement of mean HECSI compared to the baseline after 2 weeks of treatment (P = 0.029). Only mild local side effect was observed. By subjects’ evaluation, all the patients showed an improvement of clinical severity. The result can be implied that topical vitamin D analogue is safe and has the potential to be an alternative treatment for chronic hand eczema.