Journal of Advances in Health and Medical Sciences
Journal ISSN: 2517-9616
Article DOI:
Received: 15 May 2016
Accepted: 29 May 2016
Published: 24 June 2016
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  • Energy balance and its relationship with metabolic disease in Bangladeshi middle-aged women

Malik Syeda Umme Fahmida, Begum Musammat Kulsuma, Ahmad Abu Toha Reza

Published online: 2016


Obesity has been rising as a major public health challenge. The obesity epidemic is more in middle aged women in urban areas than those of rural areas. Metabolic disease has characteristic features like higher prevalence of abdominal obesity in South Asians than white Caucasians. Because of the occurrence of metabolic syndrome at a lower range of Body Mass Index (BMI) and it is proposed that cut offs for both measures of obesity should be changed to reach a new setting point for overweight BMI 23-24.9kg/m2 and ≥25 kg/m2 for obesity for South Asians. The strength and direction of energy balance (energy flux and body weight) and the development of type 2 diabetes (T2D) has not been adequately investigated. In this study nearly 2000 middle-aged Bangladeshi women were taken as a study population who had not suffered from diabetes. These women had to face interview at the initial phase and finally repeated investigation was done regularly to collect information on their metabolic risk factors. Over a period of 3.6 years follow-up, 850 new cases of T2D were documented. During follow-up 850 new cases of T2D were documented. Energy Intake (EI) was associated with increased risk, and energy expenditure with Physical Activity (PA) was associated with change in weight and decreased risk of T2D. In our population, we found women tend to develop T2D who are less active with higher EI than those of more active with lower EI. We also observed the association was more evident among overweight and obese women (BMI≥25 kg/m2). These follow up study suggest that energy balance plays a dominant role in the development of weight regulation and this effect may be modified by BMI. Body weight regulation is a complex collection and genetic variables that control energy intake and expenditure. Further study of this concept may help to achieve a healthy weight.